Varaico: Literature-Extracted Genetic Variants

MLKL

113 papers

RefSeq Summary

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activi...

Pfam Domains

MLKL_Naa 4–146UCSCMixed lineage kinase domain-like N-terminal domain

PK_Tyr_Ser-Thraa 209–466UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mixed lineage kinase domain like pseudokinase

HGNC Alias Symbol

FLJ34389

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_152649.4

p.I7S

c.20T>G

Surrounding Variants

1 paper

NM_152649.4

p.I8S

c.23T>G

1 paper

NM_152649.4

p.I8I

c.24C>A

1 paper

NM_152649.4

p.K5E

c.13A>G

1 paper

NM_152649.4

p.L10I

c.28C>A

1 paper

NM_152649.4

p.N3N

c.9T>C

1 paper

NM_152649.4

p.G11S

c.31G>A

1 paper

NM_152649.4

p.I14S

c.41T>G

1 paper

NM_152649.4

p.K16E

c.46A>G

1 paper

NM_152649.4

p.R17W

c.49C>T

1 paper

NM_152649.4

p.C18S

c.52T>A

1 paper

NM_152649.4

p.C18S

c.53G>C

4 papers

NM_152649.4

p.E19K

c.55G>A