Varaico: Literature-Extracted Genetic Variants

MMP10

119 papers

RefSeq Summary

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological proces...

Pfam Domains

PG_binding_1aa 28–86UCSCPutative peptidoglycan binding domain

Peptidase_M10aa 107–263UCSCMatrixin

Hemopexinaa 295–337UCSCHemopexin

Hemopexinaa 339–382UCSCHemopexin

Hemopexinaa 387–434UCSCHemopexin

Hemopexinaa 436–476UCSCHemopexin

Gene Aliases

HGNC Name

matrix metallopeptidase 10

HGNC Previous Symbol

STMY2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002425.3

p.E166insFs

c.497_498insA

Surrounding Variants

5 papers

NM_002425.3

p.E166Splc

c.497-2A>G

1 paper

NM_002425.3

p.L180L

c.540G>A

1 paper

NM_002425.3

p.H182Q

c.546T>A

1 paper

NM_002425.3

p.A183T

c.547G>A

1 paper

NM_002425.3

p.P185T

c.553C>A

1 paper

NM_002425.3

p.P188_G189insA

c.562_566ins3

1 paper

NM_002425.3

p.D193H

c.577G>C

1 paper

NM_002425.3

p.D193fs

c.577_578fs

1 paper

NM_002425.3

p.G192_I194delFs

c.576_580del5

3 papers

NM_002425.3

p.D199N

c.595G>A

1 paper

NM_002425.3

p.V164fs

c.490_491fs

1 paper

NM_002425.3

p.A163V

c.488C>T