Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 193 variants

33 papers

NM_001303256.3

p.S87L

c.260C>T

33 papers

NM_001303256.3

p.R252W

c.754C>T

14 papers

NM_001303256.3

p.T424R

c.1271C>G

13 papers

NM_001303256.3

p.E27K

c.79G>A

13 papers

NM_001303256.3

p.R132C

c.394C>T

12 papers

NM_001303256.3

p.Q400R

c.1199A>G

11 papers

NM_001303256.3

p.E236G

c.707A>G

11 papers

NM_001303256.3

p.D466N

c.1396G>A

9 papers

NM_001303256.3

p.R132L

c.395G>T

9 papers

NM_014941.3

p.R190W

c.568C>T

8 papers

NM_001303256.3

p.M276I

c.828G>T

8 papers

NM_001303256.3

p.M276I

c.828G>C