Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001303256.3

p.G460E

c.1379G>A

Surrounding Variants

3 papers

NM_001303256.3

p.D466H

c.1396G>C

14 papers

NM_001303256.3

p.D466N

c.1396G>A

NM_014941.3

p.D404N

c.1210G>A

6 papers

NM_001303256.3

p.D466G

c.1397A>G

1 paper

NM_014941.3

p.G407D

c.1220G>A

1 paper

NM_001303256.3

p.E482*

c.1444G>T

1 paper

NM_001303256.3

p.P494L

c.1481C>T

3 papers

NM_001303256.3

p.H446Q

c.1338C>G

3 papers

NM_001303256.3

p.H446Q

c.1338C>A

5 papers

NM_001303256.3

p.G444R

c.1330G>C

5 papers

NM_001303256.3

p.G444R

c.1330G>A

1 paper

NM_001303256.3

p.R441*

c.1321C>T

7 papers

NM_001303256.3

p.A431V

c.1292C>T