Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001303256.3

p.E422G

c.1265A>G

Surrounding Variants

16 papers

NM_001303256.3

p.T424R

c.1271C>G

NM_014941.3

p.T362R

c.1085C>G

2 papers

NM_001303256.3

p.T424K

c.1271C>A

1 paper

NM_001303256.3

p.P417L

c.1250C>T

2 papers

NM_001303256.3

p.K427R

c.1280A>G

2 papers

NM_001303256.3

p.V413A

c.1238T>C

7 papers

NM_001303256.3

p.A431V

c.1292C>T

6 papers

NM_001303256.3

p.V413F

c.1237G>T

8 papers

NM_001303256.3

p.C407Y

c.1220G>A

5 papers

NM_001303256.3

p.A406V

c.1217C>T

1 paper

NM_001303256.3

p.R441*

c.1321C>T

5 papers

NM_001303256.3

p.G444R

c.1330G>C

5 papers

NM_001303256.3

p.G444R

c.1330G>A