Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001303256.3

p.G381D

c.1142G>A

Surrounding Variants

1 paper

NM_001303256.3

p.G381A

c.1142G>C

1 paper

NM_001303256.3

p.L379V

c.1135C>G

4 papers

NM_001303256.3

p.S388R

c.1162A>C

5 papers

NM_001303256.3

p.S388R

c.1164C>G

4 papers

NM_001303256.3

p.S388R

c.1164C>A

7 papers

NM_001303256.3

p.Y394C

c.1181A>G

NM_014941.3

p.Y332C

c.995A>G

15 papers

NM_001303256.3

p.Q400R

c.1199A>G

NM_014941.3

p.Q338R

c.1013A>G

1 paper

NM_001303256.3

p.G404S

c.1210G>A

5 papers

NM_001303256.3

p.A406V

c.1217C>T

8 papers

NM_001303256.3

p.C407Y

c.1220G>A

6 papers

NM_001303256.3

p.V413F

c.1237G>T

2 papers

NM_001303256.3

p.V413A

c.1238T>C