Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001303256.3

p.M253I

c.759G>T

Surrounding Variants

1 paper

NM_001303256.3

p.M253I

c.759G>C

1 paper

NM_001303256.3

p.M253I

c.759G>A

38 papers

NM_001303256.3

p.R252W

c.754C>T

NM_014941.3

p.R190W

c.568C>T

2 papers

NM_001303256.3

p.Y248C

c.743A>G

2 papers

NM_001303256.3

p.R241R

c.723T>A

5 papers

NM_001303256.3

p.R266S

c.798G>T

6 papers

NM_001303256.3

p.R266S

c.798G>C

1 paper

NM_001303256.3

p.L267P

c.800T>C

14 papers

NM_001303256.3

p.E236G

c.707A>G

NM_014941.3

p.E174G

c.521A>G

1 paper

NM_014941.3

p.P173S

c.517C>T

1 paper

NM_001303256.3

p.K273R

c.818A>G

1 paper

NM_001303256.3

p.T228M

c.683C>T