Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001303256.3

p.F118L

c.352T>C

Surrounding Variants

1 paper

NM_001303256.3

p.I111T

c.332T>C

2 papers

NM_001303256.3

p.R110C

c.328C>T

1 paper

NM_001303256.3

p.C127R

c.379T>C

2 papers

NM_001303256.3

p.C127Y

c.380G>A

13 papers

NM_001303256.3

p.R132C

c.394C>T

12 papers

NM_001303256.3

p.R132L

c.395G>T

NM_014941.3

p.R70L

c.209G>T

1 paper

NM_001303256.3

p.R132H

c.395G>A

2 papers

NM_001303256.3

p.D141A

c.422A>C

1 paper

NM_001303256.3

p.G101G

c.303G>T

3 papers

NM_001303256.3

p.Y100H

c.298T>C

1 paper

NM_001303256.3

p.Q99H

c.297G>T

1 paper

NM_001303256.3

p.Q99H

c.297G>C