Varaico: Literature-Extracted Genetic Variants

MORC2

141 papers

RefSeq Summary

This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in rep...

Pfam Domains

HATPase_c_3aa 26–169UCSCHistidine kinase-, DNA gyrase B-, and HSP90-like ATPase

Morc6_S5aa 323–451UCSCMorc6 ribosomal protein S5 domain 2-like

zf-CWaa 495–542UCSCCW-type Zinc Finger

Gene Aliases

HGNC Name

MORC family CW-type zinc finger 2

HGNC Previous Symbol

ZCWCC1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_001303256.3

p.T25I

c.74C>T

Surrounding Variants

7 papers

NM_001303256.3

p.T24I

c.71C>T

13 papers

NM_001303256.3

p.E27K

c.79G>A

1 paper

NM_001303256.3

p.E27V

c.80A>T

2 papers

NM_001303256.3

p.E35A

c.104A>C

1 paper

NM_001303256.3

p.L36L

c.108G>A

1 paper

NM_001303256.3

p.D57N

c.169G>A

1 paper

NM_001303256.3

p.R59Q

c.176G>A

4 papers

NM_001303256.3

p.D68A

c.203A>C

1 paper

NM_001303256.3

p.D69A

c.206A>C

1 paper

NM_001303256.3

p.G70V

c.209G>T

1 paper

NM_001303256.3

p.D77H

c.229G>C

1 paper

NM_001303256.3

p.D77N

c.229G>A