Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.L31P

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.L31P
c.92T>C
Surrounding Variants
1 paper
NM_005373.3
p.L30*
c.89T>A
1 paper
NM_005373.3
p.S33P
c.97T>C
1 paper
NM_005373.3
p.S29Y
c.86C>A
1 paper
NM_005373.3
p.S33*
c.98C>A
1 paper
NM_005373.3
p.S33*
c.98C>G
1 paper
NM_005373.3
p.S29P
c.85T>C
1 paper
NM_005373.3
p.V28_S29ins2
c.84_85ins6
1 paper
NM_005373.3
p.D27E
c.81T>G
2 papers
NM_005373.3
p.E36D
c.108G>C
54 papers
NM_005373.3
p.K39N
c.117G>C
55 papers
NM_005373.3
p.K39N
c.117G>T
1 paper
NM_005373.3
p.C40S
c.118T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."