Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.G88A

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.G88A
c.263G>C
Surrounding Variants
1 paper
NM_005373.3
p.F87S
c.260T>C
13 papers
NM_005373.3
p.R90*
c.268C>T
8 papers
NM_005373.3
p.R90Q
c.269G>A
1 paper
NM_005373.3
p.R90R
c.270A>T
1 paper
NM_005373.3
p.Y91*
c.273C>A
1 paper
NM_005373.3
p.Y91*
c.273C>G
1 paper
NM_005373.3
p.Y91Y
c.273C>T
1 paper
NM_005373.3
p.V92M
c.274G>A
1 paper
NM_005373.3
p.M84I
c.252G>C
1 paper
NM_005373.3
p.M84_P85ins6
c.250_254ins18
1 paper
NM_005373.3
p.C93S
c.277T>A
1 paper
NM_005373.3
p.C93S
c.278G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."