Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.H108_L109delFs

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.H108_L109delFs
c.324_325delCC
Surrounding Variants
1 paper
NM_005373.3
p.H108P
c.323A>C
1 paper
NM_005373.3
p.H108L
c.323A>T
1 paper
NM_005373.3
p.H108Y
c.322C>T
1 paper
NM_005373.3
p.P106P
c.318G>A
66 papers
NM_005373.3
p.P106L
c.317C>T
1 paper
NM_005373.3
p.W110*
c.329G>A
1 paper
NM_005373.3
p.W110L
c.329G>T
1 paper
NM_005373.3
p.P106A
c.316C>G
2 papers
NM_005373.3
p.W110*
c.330G>A
5 papers
NM_005373.3
p.F105L
c.315T>A
5 papers
NM_005373.3
p.F105L
c.315T>G
1 paper
NM_005373.3
p.V111G
c.332T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."