Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.P136S

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.P136S
c.406C>T
Surrounding Variants
10 papers
NM_005373.3
p.P136H
c.407C>A
3 papers
NM_005373.3
p.P136R
c.407C>G
7 papers
NM_005373.3
p.P136L
c.407C>T
1 paper
NM_005373.3
p.P135R
c.404C>G
2 papers
NM_005373.3
p.S137fs
c.409_410fs
2 papers
NM_005373.3
p.P135delFs
c.403delC
1 paper
NM_005373.3
p.A134D
c.401C>A
2 papers
NM_005373.3
p.A134G
c.401C>G
1 paper
NM_005373.3
p.I138delFs
c.413delT
1 paper
NM_005373.3
p.I138fs
c.412_413fs
1 paper
NM_005373.3
p.A134P
c.400G>C
1 paper
NM_005373.3
p.A134_P135del1
c.402_404delTCC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."