Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.Q146delFs

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.Q146delFs
c.436delC
Surrounding Variants
1 paper
NM_005373.3
p.S145N
c.434G>A
1 paper
NM_005373.3
p.S145fs
c.433_434fs
1 paper
NM_005373.3
p.G144A
c.431G>C
2 papers
NM_005373.3
p.G144R
c.430G>A
1 paper
NM_005373.3
p.Q146Q
c.438G>A
2 papers
NM_005373.3
p.G144R
c.430G>C
1 paper
NM_005373.3
p.P147insFs
c.440dupC
1 paper
NM_005373.3
p.P147S
c.439C>T
1 paper
NM_005373.3
p.G144insFs
c.432dupG
1 paper
NM_005373.3
p.P147P
c.441A>T
6 papers
NM_005373.3
p.G143S
c.427G>A
1 paper
NM_005373.3
p.G148V
c.443G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."