Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.W154R

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
13 papers
NM_005373.3
p.W154R
c.460T>C
Surrounding Variants
11 papers
NM_005373.3
p.W154R
c.460T>A
1 paper
NM_005373.3
p.W154C
c.462G>T
1 paper
NM_005373.3
p.S153_E156delFs
c.457_467del11
1 paper
NM_005373.3
p.E155D
c.465G>C
1 paper
NM_005373.3
p.E155D
c.465G>T
1 paper
NM_005373.3
p.A158P
c.472G>C
2 papers
NM_005373.3
p.E149K
c.445G>A
1 paper
NM_005373.3
p.G148V
c.443G>T
1 paper
NM_005373.3
p.P147P
c.441A>T
1 paper
NM_005373.3
p.P147S
c.439C>T
1 paper
NM_005373.3
p.Q146Q
c.438G>A
1 paper
NM_005373.3
p.P147insFs
c.440dupC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."