Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.S226T

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005373.3
p.S226T
c.676T>A
Surrounding Variants
1 paper
NM_005373.3
p.S226Y
c.677C>A
1 paper
NM_005373.3
p.S226F
c.677C>T
1 paper
NM_005373.3
p.P227T
c.679C>A
1 paper
NM_005373.3
p.P227R
c.680C>G
1 paper
NM_005373.3
p.Q224P
c.671A>C
1 paper
NM_005373.3
p.R229T
c.686G>C
1 paper
NM_005373.3
p.R229insFs
c.686_687insA
2 papers
NM_005373.3
p.P222S
c.664C>T
18 papers
NM_005373.3
p.E230G
c.689A>G
6 papers
NM_005373.3
p.E230E
c.690A>G
1 paper
NM_005373.3
p.G221R
c.661G>A
3 papers
NM_005373.3
p.Q219E
c.655C>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."