Varaico: Literature-Extracted Genetic Variants

Gene:MPL
Variant:p.V501G

MPL

1,557 papers

RefSeq Summary

In 1990 an oncogene, v-mpl, was identified from the murine myeloproliferative leukemia virus that was capable of immortalizing bone marrow hematopoietic cells from different lineages. In 1992 the huma...

Pfam Domains

EpoR_lig-bindaa 25–128UCSCErythropoietin receptor, ligand binding

Gene Aliases

HGNC Name

MPL proto-oncogene, thrombopoietin receptor

HGNC Alias Symbols

CD110; TPOR; THPOR

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_005373.3
p.V501G
c.1502T>G
Surrounding Variants
22 papers
NM_005373.3
p.V501A
c.1502T>C
5 papers
NM_005373.3
p.V501M
c.1501G>A
3 papers
NM_005373.3
p.V501L
c.1501G>C
3 papers
NM_005373.3
p.V501L
c.1501G>T
1 paper
NM_005373.3
p.L502L
c.1504C>T
1 paper
NM_005373.3
p.L502delins
c.1504_1505delinsGG
1 paper
NM_005373.3
p.L500I
c.1498C>A
1 paper
NM_005373.3
p.L500fs
c.1498_1499fs
2 papers
NM_005373.3
p.L500V
c.1498C>G
5 papers
NM_005373.3
p.L500delFs
c.1499delT
3 papers
NM_005373.3
p.H499L
c.1496A>T
2 papers
NM_005373.3
p.G503A
c.1508G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."