mitochondrial ribosomal protein L48

CGI-118

mL48

Large ribosomal subunit protein mL48

39S ribosomal protein L48, mitochondrial

L48mt

MRP-L48

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Jan 2016].

Varaico: Literature-Extracted Genetic Variants

MRPL48

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols