mitochondrial ribosomal protein S27

KIAA0264

mS27

Small ribosomal subunit protein mS27

28S ribosomal protein S27, mitochondrial

Mitochondrial ribosomal protein S27

MRP-S27

S27mt

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013].

Varaico: Literature-Extracted Genetic Variants

MRPS27

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols