mitochondrial ribosomal protein S6

C21orf101

MRP-S6

RPMS6

bS6m

chromosome 21 open reading frame 101

Small ribosomal subunit protein bS6m

28S ribosomal protein S6, mitochondrial

S6mt

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S6P family. Pseudogenes corresponding to this gene are found on chromosomes 1p and 12q. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

MRPS6

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol