Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002439.5

p.R4R

c.12G>A

Surrounding Variants

1 paper

NM_002439.5

p.R4R

c.12G>C

1 paper

NM_002439.5

p.K5M

c.14A>T

3 papers

NM_002439.5

p.P6S

c.16C>T

1 paper

NM_002439.5

p.R3H

c.8G>A

1 paper

NM_002439.5

p.R3S

c.7C>A

1 paper

NM_002439.5

p.R3C

c.7C>T

1 paper

NM_002439.5

p.S2S

c.6T>C

1 paper

NM_002439.5

p.S8_G10delFs

c.22_28del7

1 paper

NM_002439.5

p.S2F

c.5C>T

1 paper

NM_002439.5

p.A7T

c.19G>A

1 paper

NM_002439.5

p.A7V

c.20C>T

3 papers

NM_002439.5

p.M1I

c.3G>A