Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002439.5

p.A7A

c.21G>A

Surrounding Variants

1 paper

NM_002439.5

p.A7V

c.20C>T

1 paper

NM_002439.5

p.S8insFs

c.23dupC

1 paper

NM_002439.5

p.S8W

c.23C>G

1 paper

NM_002439.5

p.S8L

c.23C>T

1 paper

NM_002439.5

p.A7T

c.19G>A

1 paper

NM_002439.5

p.S8S

c.24G>C

1 paper

NM_002439.5

p.S8_G10delFs

c.22_28del7

1 paper

NM_002439.5

p.G9S

c.25G>A

3 papers

NM_002439.5

p.P6S

c.16C>T

1 paper

NM_002439.5

p.G9D

c.26G>A

1 paper

NM_002439.5

p.K5M

c.14A>T

1 paper

NM_002439.5

p.L11insFs

c.32_33ins4