Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

9 papers

NM_002439.5

p.A12T

c.34G>A

Surrounding Variants

1 paper

NM_002439.5

p.A12insFs

c.34_35ins4

1 paper

NM_002439.5

p.A12S

c.34G>T

1 paper

NM_002439.5

p.L11L

c.33C>G

1 paper

NM_002439.5

p.L11L

c.33C>T

1 paper

NM_002439.5

p.L11I

c.31C>A

1 paper

NM_002439.5

p.L11F

c.31C>T

1 paper

NM_002439.5

p.L11insFs

c.32_33ins4

1 paper

NM_002439.5

p.L11_A12delFs

c.33_36del4

4 papers

NM_002439.5

p.A13A

c.39C>T

1 paper

NM_002439.5

p.G9D

c.26G>A

1 paper

NM_002439.5

p.G9S

c.25G>A

1 paper

NM_002439.5

p.S15N

c.44G>A