Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.P18P

c.54T>C

Surrounding Variants

1 paper

NM_002439.5

p.A19_Q21del0

c.55_63del9

2 papers

NM_002439.5

p.P18L

c.53C>T

1 paper

NM_002439.5

p.P18_A19delFs

c.54_57del4

1 paper

NM_002439.5

p.P18T

c.52C>A

2 papers

NM_002439.5

p.A19V

c.56C>T

1 paper

NM_002439.5

p.A17A

c.51C>T

5 papers

NM_002439.5

p.P18_A19del0

c.52_57del6

1 paper

NM_002439.5

p.A17V

c.50C>T

2 papers

NM_002439.5

p.R20K

c.59G>A

1 paper

NM_002439.5

p.A17_P18del1

c.51_53delCCC

1 paper

NM_002439.5

p.A17_A19del0

c.51_56del6

1 paper

NM_002439.5

p.Q21E

c.61C>G