Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.A22_F28del7

c.64_83del21

Surrounding Variants

1 paper

NM_002439.5

p.Q21H

c.63A>T

1 paper

NM_002439.5

p.A22T

c.64G>A

1 paper

NM_002439.5

p.Q21E

c.61C>G

1 paper

NM_002439.5

p.Q21*

c.61C>T

1 paper

NM_002439.5

p.A22V

c.65C>T

3 papers

NM_002439.5

p.A22_V23del1

c.66_68delGGT

2 papers

NM_002439.5

p.R20K

c.59G>A

2 papers

NM_002439.5

p.A19V

c.56C>T

2 papers

NM_002439.5

p.L24F

c.72G>C

2 papers

NM_002439.5

p.L24F

c.72G>T

1 paper

NM_002439.5

p.P18P

c.54T>C

1 paper

NM_002439.5

p.A19_Q21del0

c.55_63del9