Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002439.5

p.F27S

c.80T>C

Surrounding Variants

1 paper

NM_002439.5

p.R26R

c.78A>T

1 paper

NM_002439.5

p.F28V

c.82T>G

1 paper

NM_002439.5

p.R26P

c.77G>C

1 paper

NM_002439.5

p.F28Y

c.83T>A

3 papers

NM_002439.5

p.R26*

c.76C>T

1 paper

NM_002439.5

p.Q29*

c.85C>T

2 papers

NM_002439.5

p.S25N

c.74G>A

1 paper

NM_002439.5

p.Q29Q

c.87G>A

2 papers

NM_002439.5

p.L24F

c.72G>C

2 papers

NM_002439.5

p.L24F

c.72G>T

1 paper

NM_002439.5

p.S30A

c.88T>G

1 paper

NM_002439.5

p.S30F

c.89C>T