Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.G32R

c.94G>A

Surrounding Variants

1 paper

NM_002439.5

p.G32R

c.94G>C

4 papers

NM_002439.5

p.T31T

c.93G>A

1 paper

NM_002439.5

p.G32E

c.95G>A

1 paper

NM_002439.5

p.T31T

c.93G>T

1 paper

NM_002439.5

p.S33delFs

c.97delA

1 paper

NM_002439.5

p.S33_S36del4

c.97_107del12

1 paper

NM_002439.5

p.S33R

c.97A>C

1 paper

NM_002439.5

p.S33N

c.98G>A

1 paper

NM_002439.5

p.S30F

c.89C>T

1 paper

NM_002439.5

p.S30A

c.88T>G

1 paper

NM_002439.5

p.Q29Q

c.87G>A

1 paper

NM_002439.5

p.Q29*

c.85C>T