Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.S39Y

c.116C>A

Surrounding Variants

2 papers

NM_002439.5

p.S40P

c.118T>C

2 papers

NM_002439.5

p.S38F

c.113C>T

2 papers

NM_002439.5

p.T41I

c.122C>T

1 paper

NM_002439.5

p.T37I

c.110C>T

1 paper

NM_002439.5

p.T37P

c.109A>C

1 paper

NM_002439.5

p.G42D

c.125G>A

1 paper

NM_002439.5

p.K35I

c.104A>T

2 papers

NM_002439.5

p.A43A

c.129A>G

2 papers

NM_002439.5

p.A44T

c.130G>A

1 paper

NM_002439.5

p.D45H

c.133G>C

1 paper

NM_002439.5

p.S33N

c.98G>A

1 paper

NM_002439.5

p.S33R

c.97A>C