Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.A54ins3

c.161_162ins9

Surrounding Variants

1 paper

NM_002439.5

p.A54_A62ins3

c.160_186dup27

18 papers

NM_002439.5

p.A54_A60del0

c.162_179del18

1 paper

NM_002439.5

p.A52P

c.154G>C

1 paper

NM_002439.5

p.A52insFs

c.155_156insG

5 papers

NM_002439.5

p.A51S

c.151G>T

1 paper

NM_002439.5

p.A53_A55del0

c.159_164del6

1 paper

NM_002439.5

p.G50_A51ins1

c.150_151insGCT

3 papers

NM_002439.5

p.A54_A57ins1

c.162_170dup9

5 papers

NM_002439.5

p.A54_A57del0

c.162_170del9

1 paper

NM_002439.5

p.A51_A56del0

c.151_168del18

2 papers

NM_002439.5

p.A53T

c.157G>A

1 paper

NM_002439.5

p.G50A

c.149G>C