Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_002439.5

p.A54A

c.162T>C

Surrounding Variants

4 papers

NM_002439.5

p.A62_P63ins3

c.186_187ins9

1 paper

NM_002439.5

p.A57_A62ins2

c.169_186dup18

1 paper

NM_002439.5

p.A54delins

c.162delinsTTCATCGGCC

2 papers

NM_002439.5

p.A60_A62del0

c.178_186del9

1 paper

NM_002439.5

p.A55_P63del0

c.163_189del27

2 papers

NM_002439.5

p.A54_P64delins

c.162_190delinsCG

1 paper

NM_002439.5

p.A54_P64delins

c.162_192delinsCGCC

1 paper

NM_002439.5

p.A54_A55insFs

c.162_163dupTG

1 paper

NM_002439.5

p.A55T

c.163G>A

1 paper

NM_002439.5

p.A55_P64del0

c.164_190del27

1 paper

NM_002439.5

p.A54_P63del0

c.162_188del27

1 paper

NM_002439.5

p.A56_A60del0

c.168_179del12