Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.A62_P63ins3

c.186_187ins9

Surrounding Variants

4 papers

NM_002439.5

p.A61P

c.181G>C

12 papers

NM_002439.5

p.A65_A68ins1

c.195_203dup9

1 paper

NM_002439.5

p.A61ins9

c.181_182ins27

1 paper

NM_002439.5

p.P63_P64ins6

c.189_190ins18

4 papers

NM_002439.5

p.A61_P64del0

c.182_190del9

3 papers

NM_002439.5

p.A61G

c.182C>G

1 paper

NM_002439.5

p.A61V

c.182C>T

13 papers

NM_002439.5

p.A60P

c.178G>C

19 papers

NM_002439.5

p.A61_P63ins1

c.181_189dup9

1 paper

NM_002439.5

p.P63_P64ins6

c.189_190ins18

6 papers

NM_002439.5

p.A62_P63ins6

c.186_187ins18

1 paper

NM_002439.5

p.A62_P63ins3

c.186_187ins9