Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.P63S

c.187C>T

Surrounding Variants

2 papers

NM_002439.5

p.P63_P64insAAP

c.187_191ins9

1 paper

NM_002439.5

p.P63_P64ins6

c.187_191ins18

8 papers

NM_002439.5

p.P63A

c.187C>G

11 papers

NM_002439.5

p.P64A

c.190C>G

1 paper

NM_002439.5

p.A62_P63ins6

c.184_188ins18

1 paper

NM_002439.5

p.A62S

c.184G>T

1 paper

NM_002439.5

p.P64_A65ins3

c.192_193ins9

3 papers

NM_002439.5

p.A61G

c.182C>G

1 paper

NM_002439.5

p.A61V

c.182C>T

1 paper

NM_002439.5

p.A65T

c.193G>A

4 papers

NM_002439.5

p.A61P

c.181G>C

1 paper

NM_002439.5

p.A62_P63ins3

c.186_187ins9