Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.P67fs

c.199_200fs

Surrounding Variants

4 papers

NM_002439.5

p.P67A

c.199C>G

1 paper

NM_002439.5

p.P67L

c.200C>T

1 paper

NM_002439.5

p.A68_P69delFs

c.204_207del4

1 paper

NM_002439.5

p.A68insFs

c.203_204ins8

15 papers

NM_002439.5

p.P67_P69del0

c.199_207del9

1 paper

NM_002439.5

p.A65_F71delFs

c.195_211del17

4 papers

NM_002439.5

p.A68A

c.204T>G

1 paper

NM_002439.5

p.F71_P77insFs

c.211_230dup20

1 paper

NM_002439.5

p.P69A

c.205C>G

1 paper

NM_002439.5

p.P69S

c.205C>T

1 paper

NM_002439.5

p.A65T

c.193G>A

1 paper

NM_002439.5

p.A65_P66ins3

c.193_197ins9