Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

20 papers

NM_002439.5

p.K349*

c.1045A>T

Surrounding Variants

2 papers

NM_002439.5

p.D351N

c.1051G>A

1 paper

NM_002439.5

p.D351G

c.1052A>G

1 paper

NM_002439.5

p.P346H

c.1037C>A

2 papers

NM_002439.5

p.P346L

c.1037C>T

1 paper

NM_002439.5

p.N345K

c.1035T>A

1 paper

NM_002439.5

p.N345K

c.1035T>G

2 papers

NM_002439.5

p.N345delFs

c.1035delT

1 paper

NM_002439.5

p.A353T

c.1057G>A

1 paper

NM_002439.5

p.V354fs

c.1060_1061fs

2 papers

NM_002439.5

p.D343Splc

c.1028-1A>T

1 paper

NM_002439.5

p.N355I

c.1064A>T

1 paper

NM_002439.5

p.V356I

c.1066G>A