Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.V356L

c.1066G>C

Surrounding Variants

1 paper

NM_002439.5

p.V356I

c.1066G>A

1 paper

NM_002439.5

p.N355I

c.1064A>T

1 paper

NM_002439.5

p.E358delFs

c.1073delA

1 paper

NM_002439.5

p.V354fs

c.1060_1061fs

1 paper

NM_002439.5

p.I359insFs

c.1076_1077insT

1 paper

NM_002439.5

p.I359L

c.1075A>C

2 papers

NM_002439.5

p.I359L

c.1075A>T

1 paper

NM_002439.5

p.A353T

c.1057G>A

1 paper

NM_002439.5

p.D351G

c.1052A>G

2 papers

NM_002439.5

p.D351N

c.1051G>A

1 paper

NM_002439.5

p.D362N

c.1084G>A

1 paper

NM_002439.5

p.T363insFs

c.1087dupA