Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.T363insFs

c.1087dupA

Surrounding Variants

1 paper

NM_002439.5

p.T363S

c.1087A>T

1 paper

NM_002439.5

p.T363N

c.1088C>A

1 paper

NM_002439.5

p.T363I

c.1088C>T

1 paper

NM_002439.5

p.D362N

c.1084G>A

1 paper

NM_002439.5

p.S364F

c.1091C>T

1 paper

NM_002439.5

p.T365I

c.1094C>T

1 paper

NM_002439.5

p.I359insFs

c.1076_1077insT

1 paper

NM_002439.5

p.I359L

c.1075A>C

2 papers

NM_002439.5

p.I359L

c.1075A>T

1 paper

NM_002439.5

p.S366I

c.1097G>T

1 paper

NM_002439.5

p.Y367N

c.1099T>A

1 paper

NM_002439.5

p.Y367delFs

c.1100delA