Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.I611insFs

c.1831_1832insA

Surrounding Variants

1 paper

NM_002439.5

p.Q610*

c.1828C>T

1 paper

NM_002439.5

p.E612K

c.1834G>A

1 paper

NM_002439.5

p.G609_I611delFs

c.1827_1831del5

1 paper

NM_002439.5

p.G609_I611del3

c.1825_1832del9

1 paper

NM_002439.5

p.H614N

c.1840C>A

1 paper

NM_002439.5

p.V607E

c.1820T>A

1 paper

NM_002439.5

p.S606G

c.1816A>G

1 paper

NM_002439.5

p.L615P

c.1844T>C

2 papers

NM_002439.5

p.R616C

c.1846C>T

1 paper

NM_002439.5

p.S605F

c.1814C>T

1 paper

NM_002439.5

p.R616H

c.1847G>A

1 paper

NM_002439.5

p.S605A

c.1813T>G