Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.E886G

c.2657A>G

Surrounding Variants

4 papers

NM_002439.5

p.D887N

c.2659G>A

1 paper

NM_002439.5

p.D887Y

c.2659G>T

2 papers

NM_002439.5

p.S888*

c.2663C>A

2 papers

NM_002439.5

p.S888*

c.2663C>G

1 paper

NM_002439.5

p.R890_V891delFs

c.2670_2671delAG

1 paper

NM_002439.5

p.R890G

c.2668A>G

1 paper

NM_002439.5

p.S885_E886Splc

c.2656-10T>C

1 paper

NM_002439.5

p.V891I

c.2671G>A

1 paper

NM_002439.5

p.V891E

c.2672T>A

1 paper

NM_002439.5

p.M892V

c.2674A>G

1 paper

NM_002439.5

p.M892I

c.2676G>A

1 paper

NM_002439.5

p.M892I

c.2676G>C