Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.G901V

c.2702G>T

Surrounding Variants

1 paper

NM_002439.5

p.G901E

c.2702G>A

1 paper

NM_002439.5

p.G900D

c.2699G>A

1 paper

NM_002439.5

p.G900S

c.2698G>A

1 paper

NM_002439.5

p.S903G

c.2707A>G

1 paper

NM_002439.5

p.M899fs

c.2695_2696fs

2 papers

NM_002439.5

p.M899delFs

c.2695_2696delAT

1 paper

NM_002439.5

p.N898H

c.2692A>C

1 paper

NM_002439.5

p.Y905D

c.2713T>G

1 paper

NM_002439.5

p.P897S

c.2689C>T

1 paper

NM_002439.5

p.G896E

c.2687G>A

3 papers

NM_002439.5

p.G896R

c.2686G>A

3 papers

NM_002439.5

p.G896R

c.2686G>C