Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.Q908L

c.2723A>T

Surrounding Variants

1 paper

NM_002439.5

p.Q908P

c.2723A>C

1 paper

NM_002439.5

p.Q908R

c.2723A>G

1 paper

NM_002439.5

p.Q908E

c.2722C>G

1 paper

NM_002439.5

p.Q908*

c.2722C>T

1 paper

NM_002439.5

p.V909A

c.2726T>C

1 paper

NM_002439.5

p.A910T

c.2728G>A

1 paper

NM_002439.5

p.A910G

c.2729C>G

1 paper

NM_002439.5

p.A910V

c.2729C>T

11 papers

NM_002439.5

p.L911V

c.2731T>G

1 paper

NM_002439.5

p.L911S

c.2732T>C

25 papers

NM_002439.5

p.L911W

c.2732T>G

1 paper

NM_002439.5

p.Y905D

c.2713T>G