Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.P923L

c.2768C>T

Surrounding Variants

1 paper

NM_002439.5

p.A924E

c.2771C>A

1 paper

NM_002439.5

p.A924V

c.2771C>T

1 paper

NM_002439.5

p.E925K

c.2773G>A

1 paper

NM_002439.5

p.E925G

c.2774A>G

3 papers

NM_002439.5

p.Y921fs

c.2761_2762fs

1 paper

NM_002439.5

p.E926*

c.2776G>T

1 paper

NM_002439.5

p.S920F

c.2759C>T

1 paper

NM_002439.5

p.S920fs

c.2758_2759fs

10 papers

NM_002439.5

p.S920delFs

c.2760delC

1 paper

NM_002439.5

p.A927T

c.2779G>A

1 paper

NM_002439.5

p.A927V

c.2780C>T

2 papers

NM_002439.5

p.G919D

c.2756G>A