Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.I931_D933del0

c.2792_2797del6

Surrounding Variants

2 papers

NM_002439.5

p.G930E

c.2789G>A

2 papers

NM_002439.5

p.V932M

c.2794G>A

1 paper

NM_002439.5

p.G930W

c.2788G>T

1 paper

NM_002439.5

p.I929T

c.2786T>C

1 paper

NM_002439.5

p.I929V

c.2785A>G

1 paper

NM_002439.5

p.D933Y

c.2797G>T

1 paper

NM_002439.5

p.D933fs

c.2797_2798fs

1 paper

NM_002439.5

p.D933delFs

c.2799delT

1 paper

NM_002439.5

p.T928K

c.2783C>A

1 paper

NM_002439.5

p.G934S

c.2800G>A

1 paper

NM_002439.5

p.G934D

c.2801G>A

1 paper

NM_002439.5

p.A927A

c.2781G>T