Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.I935fs

c.2803_2804fs

Surrounding Variants

1 paper

NM_002439.5

p.I935delFs

c.2803delA

1 paper

NM_002439.5

p.G934D

c.2801G>A

1 paper

NM_002439.5

p.G934S

c.2800G>A

1 paper

NM_002439.5

p.F936_T937delFs

c.2808_2811del4

1 paper

NM_002439.5

p.D933delFs

c.2799delT

1 paper

NM_002439.5

p.F936F

c.2808C>T

1 paper

NM_002439.5

p.D933Y

c.2797G>T

1 paper

NM_002439.5

p.D933fs

c.2797_2798fs

1 paper

NM_002439.5

p.T937I

c.2810C>T

1 paper

NM_002439.5

p.R938_M939insT

c.2812_2816ins3

1 paper

NM_002439.5

p.R938fs

c.2812_2813fs

2 papers

NM_002439.5

p.V932M

c.2794G>A