Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

52 papers

NM_002439.5

p.A1045T

c.3133G>A

Surrounding Variants

1 paper

NM_002439.5

p.G1044D

c.3131G>A

1 paper

NM_002439.5

p.Q1048*

c.3142C>T

1 paper

NM_002439.5

p.Q1048R

c.3143A>G

1 paper

NM_002439.5

p.P1050R

c.3149C>G

1 paper

NM_002439.5

p.P1050L

c.3149C>T

1 paper

NM_002439.5

p.D1051N

c.3151G>A

1 paper

NM_002439.5

p.L1056F

c.3166C>T

6 papers

NM_002439.5

p.R1061G

c.3181A>G

1 paper

NM_002439.5

p.R1061K

c.3182G>A

1 paper

NM_002439.5

p.R1061I

c.3182G>T

3 papers

NM_002439.5

p.G1062R

c.3184G>A

3 papers

NM_002439.5

p.G1062R

c.3184G>C