Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002439.5

p.G1062R

c.3184G>C

Surrounding Variants

3 papers

NM_002439.5

p.G1062R

c.3184G>A

1 paper

NM_002439.5

p.R1061K

c.3182G>A

1 paper

NM_002439.5

p.R1061I

c.3182G>T

6 papers

NM_002439.5

p.R1061G

c.3181A>G

1 paper

NM_002439.5

p.I1063V

c.3187A>G

1 paper

NM_002439.5

p.I1063T

c.3188T>C

1 paper

NM_002439.5

p.A1064T

c.3190G>A

1 paper

NM_002439.5

p.A1065T

c.3193G>A

1 paper

NM_002439.5

p.A1065V

c.3194C>T

1 paper

NM_002439.5

p.A1065A

c.3195A>G

1 paper

NM_002439.5

p.R1066W

c.3196A>T

1 paper

NM_002439.5

p.R1066K

c.3197G>A