Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.D1077N

c.3229G>A

Surrounding Variants

1 paper

NM_002439.5

p.A1076_D1077insT

c.3226_3230ins3

1 paper

NM_002439.5

p.P1079L

c.3236C>T

1 paper

NM_002439.5

p.K1074E

c.3220A>G

1 paper

NM_002439.5

p.K1074*

c.3220A>T

3 papers

NM_002439.5

p.E1081K

c.3241G>A

1 paper

NM_002439.5

p.V1072M

c.3214G>A

1 paper

NM_002439.5

p.Y1068H

c.3202T>C

1 paper

NM_002439.5

p.A1087T

c.3259G>A

1 paper

NM_002439.5

p.R1066K

c.3197G>A

1 paper

NM_002439.5

p.R1066M

c.3197G>T

1 paper

NM_002439.5

p.R1066W

c.3196A>T

1 paper

NM_002439.5

p.A1065A

c.3195A>G