Varaico: Literature-Extracted Genetic Variants

MSH3

1,102 papers

RefSeq Summary

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch ...

Pfam Domains

MutS_Iaa 230–343UCSCMutS domain I

MutS_IIaa 366–523UCSCMutS domain II

MutS_IIIaa 540–838UCSCMutS domain III

MutS_Vaa 892–1094UCSCMutS domain V

Gene Aliases

HGNC Name

mutS homolog 3

HGNC Alias Symbols

DUP; MRP1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002439.5

p.N1098fs

c.3292_3293fs

Surrounding Variants

1 paper

NM_002439.5

p.G1095R

c.3283G>A

1 paper

NM_002439.5

p.G1095R

c.3283G>C

1 paper

NM_002439.5

p.E1094K

c.3280G>A

1 paper

NM_002439.5

p.R1101Splc

c.3302+4A>C

1 paper

NM_002439.5

p.E1092fs

c.3274_3275fs

1 paper

NM_002439.5

p.S1090L

c.3269C>T

1 paper

NM_002439.5

p.K1089*

c.3265A>T

1 paper

NM_002439.5

p.A1087T

c.3259G>A

3 papers

NM_002439.5

p.E1081K

c.3241G>A

1 paper

NM_002439.5

p.P1079L

c.3236C>T

1 paper

NM_002439.5

p.D1077N

c.3229G>A

1 paper

NM_002439.5

p.A1076_D1077insT

c.3226_3230ins3