methionine sulfoxide reductase B3

DFNB74

FLJ36866

DKFZp686C1178

deafness, autosomal recessive 74

Methionine-R-sulfoxide reductase B3

MsrB3

The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010].

Varaico: Literature-Extracted Genetic Variants

MSRB3

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol