Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.P684S

c.2050C>T

Surrounding Variants

1 paper

NM_002447.4

p.Q690*

c.2068C>T

1 paper

NM_002447.4

p.G694R

c.2080G>C

1 paper

NM_002447.4

p.R696W

c.2086C>T

1 paper

NM_002447.4

p.R696P

c.2087G>C

1 paper

NM_002447.4

p.R696Q

c.2087G>A

1 paper

NM_002447.4

p.E705K

c.2113G>A

1 paper

NM_002447.4

p.S710fs

c.2128_2129fs

1 paper

NM_002447.4

p.S714C

c.2140A>T

1 paper

NM_002447.4

p.R715W

c.2143C>T

1 paper

NM_002447.4

p.L718V

c.2152C>G

1 paper

NM_002447.4

p.E723G

c.2168A>G

1 paper

NM_002447.4

p.S674F

c.2021C>T