Varaico: Literature-Extracted Genetic Variants

MST1R

329 papers

RefSeq Summary

This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta su...

Pfam Domains

Semaaa 321–504UCSCSema domain

PSIaa 526–568UCSCPlexin repeat

TIGaa 569–674UCSCIPT/TIG domain

TIGaa 684–766UCSCIPT/TIG domain

TIGaa 770–859UCSCIPT/TIG domain

PK_Tyr_Ser-Thraa 1082–1341UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

macrophage stimulating 1 receptor

HGNC Previous Symbols

RON; PTK8; SEA

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002447.4

p.L642Q

c.1925T>A

Surrounding Variants

1 paper

NM_002447.4

p.C640G

c.1918T>G

1 paper

NM_002447.4

p.G651A

c.1952G>C

1 paper

NM_002447.4

p.R631Q

c.1892G>A

1 paper

NM_002447.4

p.P628fs

c.1882_1883fs

1 paper

NM_002447.4

p.T660A

c.1978A>G

1 paper

NM_002447.4

p.P664L

c.1991C>T

1 paper

NM_002447.4

p.K666E

c.1996A>G

1 paper

NM_002447.4

p.R669W

c.2005C>T

8 papers

NM_002447.4

p.V670G

c.2009T>G

1 paper

NM_002447.4

p.S674F

c.2021C>T

1 paper

NM_002447.4

p.P684S

c.2050C>T

1 paper

NM_002447.4

p.Q690*

c.2068C>T